Hub genes analysis
WebConclusion. Our bioinformatics analysis was based on the gene expression dataset obtained from the GEO database and identified 10 hub genes that are differentially expressed between normal myocardium and infarcted myocardium: MMP-9, Il6, Spp1, Ptgs2, Serpine1, Plaur, Cxcl5, Lgals3, Serpinb2, and Cd14. WebAdditionally, a WGCNA was used to construct a gene co-expression network, and hub genes were further identified by identifying modules related to the clinical traits of PE-IUGR. Results: Nine genes, i.e., TDRKH , XPOT , AMACR , NBN , ALS2 , CLYBL , CENPQ , PCGF6 and COQ3 were obtained by the WGCNA.
Hub genes analysis
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WebThe .gov method it’s official. Federal government websites much end in .gov or .mil. Earlier sharing sensitive information, make sure you’re on a federal government site. Web28 mrt. 2024 · Common genes were introduced into Metascape database for protein-protein interaction and functional enrichment analysis. We constructed the miRNAs-mRNAs network with the hub genes. Moreover, gene expression profiles of peripheral blood mononuclear cells (PBMCs) from peripheral blood of patients with plaque rupture were …
Web5 jun. 2024 · Functional enrichment analysis showed that the hub genes were related to NAFLD pathway and oxidative phosphorylation. Independent dataset-based analysis … Web1 apr. 2024 · Screening-stage specific module and hub-gene using WGCNA. By WGCNA analysis, we identified a variety-specific module at different stages. At the T1 stage, many genes encoding plant-hormone signal-transduction proteins and transcription factors were highly expressed in this module. We identified four WRKY family transcription factors ...
Web31 jan. 2024 · The hub genes ( 33) in key positions in the PPI network were screened with a variety of algorithms through the cytoHubba plug-in of Cytoscape ( 34 ). The obtained hub genes were reintroduced into the STRING website to determine the PPI interaction ( 35 ). Results Other Section Results of the downloaded data Web7 sep. 2024 · Hierarchical clustering of the hub genes was performed as indicated in the clustering heat map (Fig. 7a); these hub genes could well distinguish the IgAN and …
Web13 apr. 2024 · Pathway analysis revealed that the Wnt signaling pathway may be responsible for horn development. Further, through combining the protein–protein interaction networks of the DEGs, it was found that the top five hub genes, namely, ACAN, SFRP2, SFRP4, WNT3, and WNT7B, were also associated with horn development.
Web2 jul. 2024 · The hub genes were assessed by GO functional annotation analysis and visualized in a network map. Analysis of Immune Cell Infiltration We uploaded the gene … radix isoscan-h user manualWebTranscriptome profiling and network pathway analysis of genes associated with invasive phenotype in oral cancer. / Kang, Chung Jan ; Chen, Yin Ju ; Liao, Chun Ta 等. 於: Cancer Letters , 卷 284, 編號 2, 01.11.2009, p. 131-140. radix ispWeb9 apr. 2024 · Sci-Hub Comprehensive analysis of the expression and prognosis for TFAP2 in human lung carcinoma. Genes & Genomics 10.1007/s13258-020-00948-2 sci hub to open science ↓ save Cheng, C., Ai, Z., & Zhao, L. (2024). Comprehensive analysis of the expression and prognosis for TFAP2 in human lung carcinoma. radix in pythonWeb4 apr. 2024 · The team show that hub genes are conserved in other organisms and suggest that their normal function is to act as genetic buffers, minimizing the effects of mutations in other genes. Further development of genetic interaction maps should help to identify other members of this key class of genes. radix internationalWebthey may di er in terms of biological plausibility or clinical utility. Gene ontology information can be useful for further prioritizing intramodular hub genes. Examples of biological studies that show the importance of intramodular hub genes can be found reported in [4, 1, 2, 3, 5]. A ow chart of a typical network analysis is shown in Fig. 1 ... radix in latinWeb17 mei 2024 · Gene-pathway network analysis To further investigate the developmental mechanisms of CC, EC and VC, the hub genes were mapped into a crosstalk network. … radix investmentsWebSubsequently, another plug-in of Cytoscape, cytohubba was used for hub genes identification. From the whole PPI network, six hub genes (CD3D, CD3E, CD3G, FYN, GRAP2 and ITK) were screened out according to the ranking by MMC method. The sub-network of the identified hub genes is shown in Figure 4F. TCGA Survival Analysis and … radix interactive greeley